02771nas a2200265   4500008004100000245011700041210006900158260000800227300001400235490000700249520174500256653001802001653001702019653004002036653000802076653001402084653001402098653003102112653001102143653002202154653003602176653001602212100001702228856026002245       2000                        eng d00aDistribution and taxonomic implications of some phenolics in the family Lamiaceae determined by ESR spectroscopy0 aDistribution and taxonomic implications of some phenolics in the  cJan  a229–2530 v283 aThe dihydric phenolics from the leaves of 365 specimens representing 355 species and varieties of 110 genera of Lamiaceae (Labiatae) have been examined as semiquinones by ESR spectroscopy. Of these 89 genera comprising 194 species belong to the Lamiaceae, whereas 21 genera comprising 161 species have been transferred from the Verbenaceae in the most recent classification. Two chemical characters give strong support to the subfamily division of the Lamiaceae as recognised by Erdtman (1945). (Svensk Bet. Tidskr. 29, 279-285) and others. Rosmarinic acid was observed in 110 species out of 127 studied and confined to the subfamily Nepetoideae sensu Erdtman. These species produce tricolpate pollen grains. 3,4-Dihydroxyphenylethanoid glycosides were observed in 111 species all confined to Lamioideae sensu Erdtman with hexacolpate pollen grains. The acid and the phenylethanoid glycosides were found to be mutually exclusive, apart from one species, Teucrium scorodonia. A compound tentatively assigned as a beta-hydroxy-(3,4-dihydroxyphenyl) ethanoid glycoside, was observed in 49 species, solely confined to subfamily Lamioideae. Furthermore, rosmarinic acid was observed in Aegiphila mollis and in Hymenopyramis brachiata, both belonging to Lamioideae. No phenylethanoid glycosides were observed from any of 5 Hymenopyramis or from any of 30 species of Vitex. The latter result questions the transfer of the genus to Lamiaceae, but strengthens its isolated position. Chlorogenic acid was observed in 34 species and protochatechuic acid in 16 species. Hydroquinone is scattered in the family (4 species) and thymohydroquinone was observed in 7 species all belong to the Nepetoideae. (C) 2000 Elsevier Science Ltd. All rights reserved.10aChemotaxonomy10aConstituents10aDihydroxy-Phenylethanoid Glycosides10aEsr10aLamiaceae10aPhenolics10aPhenylpropanoid Glycosides10aPlants10aPollen Morphology10aRosmarinic And Chlorogenic Acid10aVerbenaceae1 aPedersen, JA  uhttp://apps.isiknowledge.com/InboundService.do?product=WOS&action=retrieve&SrcApp=Papers&UT=000085500300004&SID=2AFL5dnj5MCc8JPedL5&SrcAuth=mekentosj&mode=FullRecord&customersID=mekentosj&DestFail=http%253A%252F%252Faccess.isiproducts.com%252Fcustom_image03755nas a2200265   4500008004100000245013400041210006900175260000800244300001400252490000700266520271500273653001602988653002403004653001703028653001503045653002303060653001503083653002603098653001603124653003203140653002003172653001703192100002003209856026003229       2008                        eng d00aAntioxidant Activity of Extracts and Different Solvent Fractions of Glechoma hederacea L. and Orthosiphon stamineus (Benth.) Kudo0 aAntioxidant Activity of Extracts and Different Solvent Fractions  cJan  a615–6240 v173 aBackground. Orthosiphon stamineus is a popular medicinal plant from tropical Asia consumed in the form of infusions. Glechoma hederacea, once popular as a medicinal plant and as a bitter beer supplement, is a ubiquitous weed growing wild in moderate climates of Eurasia. Both plants belong to the Nepetoideae subfamily and are rich in phenolic antioxidants such as rosmarinic acid and flavonoids. Antioxidant activity can contribute to their traditional uses in phytotherapy as well as to their preventive value in degenerative and life-style diseases.Objectives. Two medicinal Lamiaceae species were chosen to test their antioxidant potential using three complementary assays. Preliminary screening for total polyphenols and phenolic acids was also performed to find correlations with the activity. Fractionation of the crude extract was carried out to reveal the contributions of compounds of different polarity to total antioxidant status. Interspecific variation was also analyzed.Material and Methods. Aqueous methanol extracts were prepared by reflux extraction from Orthosiphonis folium and Glechomae herba. The extracts were fractionated using liquid-liquid extraction (LLE) with petroleum ether (PE), dichloromethane (DCM), ethyl acetate (EA), and n-butanol (BuOH). All extracts and fractions were studied for their antioxidant activity using spectrophotometric assays: DPPH scavenging, phosphomolybdenum reduction, and deoxyribose degradation assay. Polyphenol content was studied by the Folin-Ciocalteu method, Arnow reaction, and Lopez-Arnaldos assay.Results. Predictably, both species possess remarkable antioxidant capacity, but the relative differences between the species and fractions depended on the applied assay. Varying correlation of total polyphenol content and the amounts of various chemical classes of polyphenols was also observed depending on the mechanism of antioxidant testing. In O. stamineus, partitioning the crude extract led to distribution of the initially very high activity among the DCM, EA, and butanol fractions, whereas in G. hederacea the moderate activity of the methanol extract was greatly enhanced in the EA and butanol fractions, which were the strongest in all assays.Conclusions. These plants can provide efficient antioxidant protection by complementary mechanisms such as free radical scavenging and metal ion reduction. However, Orthosiphonis herba is more effective as an integral extract due to the synergistic action of its components, while Glechomae herba needs fortification by fractioning the crude extract into polar solvents to increase the proportion of rosmarinic acid, the most active agent in this herb (Adv Clin Exp Med 2008, 17, 6, 615-624).10aAntioxidant10aBiological-Activity10aConstituents10aFlavonoids10aGlechoma Hederacea10aGlycosides10aOrthosiphon Stamineus10aPolyphenols10aRadical-Scavenging Activity10aRosmarinic Acid10aWhole Plants1 aMatkowski, Adam  uhttp://apps.isiknowledge.com/InboundService.do?product=WOS&action=retrieve&SrcApp=Papers&UT=000263690700004&SID=2AFL5dnj5MCc8JPedL5&SrcAuth=mekentosj&mode=FullRecord&customersID=mekentosj&DestFail=http%253A%252F%252Faccess.isiproducts.com%252Fcustom_image02114nas a2200253   4500008004100000245013500041210006900176260000800245300001100253490000800264520128200272653001001554653001701564653001401581653002201595653001401617653001201631653001301643653001501656653001601671653001101687100003301698856012901731       2007                        eng d00aUsing amplified fragment length polymorphism (AFLP) to unravel species relationships and delimitations in Minthostachys (Labiatae)0 aUsing amplified fragment length polymorphism AFLP to unravel spe  cJan  a9–190 v1533 aMinthostachys (Benth.) Spach (Labiatae) is a South American genus of aromatic shrubs frequently collected as a condiment, for the preparation of tea, or for medicinal purposes. Notoriously difficult species delimitation, conflicting taxonomic treatments of the past, and the lack of a revision with modern methods have hampered the understanding of this ecologically and economically interesting group. The amplified fragment length polymorphism (AFLP) study presented in this paper supplements field and morphological studies within the framework of a taxonomic and systematic revision. AFLP is found to be unsuitable for the reconstruction of the phylogeny of Minthostachys. Although, in some cases, morphologically well-defined species are also genetically distinct, extensive gene flow seems to occur between strikingly different species growing in the immediate vicinity and even between Minthostachys and Clinopodium (Xenopoma) vanum. Samples from the most complicated species, M. mollis, are genetically very heterogeneous and mostly fall into two clusters according to their geographical origin, exhibiting a high discrepancy with the pattern of morphological variation. (c) 2007 The Linnean Society of London, Botanical Journal of the Linnean Society, 2007, 153, 9-19.10aAndes10aConstituents10aEvolution10aGenetic-Variation10aLamiaceae10aMarkers10aMentheae10aMorphology10aNeotropical10aPlants1 aSchmidt-Lebuhn, Alexander, N  uhttps://lamiaceae.myspecies.info/content/using-amplified-fragment-length-polymorphism-aflp-unravel-species-relationships-and01701nas a2200349   4500008004100000245008600041210006900127260000800196300001400204490000700218520055300225653001800778653001700796653001700813653002300830653000900853653001300862653001400875653000900889653001900898653002800917653002300945653002500968653002600993653001801019653001701037100001601054700001301070700001501083700001301098856024001111       2006                        eng d00aStudy of the oleanolic and ursolic acid contents of some species of the Lamiaceae0 aStudy of the oleanolic and ursolic acid contents of some species  cJan  a392–3960 v343 aThe oleanolic and ursolic acid contents from 88 taxa. of Lamiaceae (19 genera, 66 species, 8 subspecies, 9 varieties and 5 hybrids) were investigated using gas chromatography. Both triterpenoid acids were present in all of the investigated taxa, but the plants belonging in the subfamily Nepetoideae produced significantly higher amounts than those in the subfamily Lamioideae. The oleanolic acid content ranged from traces to 1.840% dry weight, and that of ursolic acid from traces to 4.019% dry weight. (c) 2006 Elsevier Ltd. All rights reserved.10aChemotaxonomy10aConstituents10aDiterpenoids10aGas Chromatography10aHerb10aLabiatae10aLamiaceae10aMice10aOleanolic Acid10aPentacyclic Triterpenes10aSalvia-Officinalis10aSubfamily Lamioideae10aSubfamily Nepetoideae10aTriterpenoids10aUrsolic Acid1 aJanicsak, G1 aVeres, K1 aKakasy, AZ1 aMathe, I  uhttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T4R-4JCBPHY-1&_user=2139813&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000054276&_version=1&_urlVersion=0&_userid=2139813&md5=0fa9d49fb0d0eed1c4653613967dc834