@article {451,
	title = {Morphological, genetic and phytochemical variation of the endemic Teucrium arduini L. (Lamiaceae).},
	journal = {Phytochemistry},
	volume = {116},
	year = {2015},
	month = {2015 Aug},
	pages = {111-9},
	abstract = {<p>Analysis of the morphological traits of leaves, genetic variability (analyzed by AFLP) and chemical composition of essential oils (analyzed by GC-MS) was conducted on eleven populations of the endemic Illyric-Balcanic species Teucrium arduini L. in Croatia, Bosnia and Herzegovina, and Montenegro. Average blade length and width ranged from 20.00 to 31.47mm and from 11.58 to 15.66mm, respectively. Multivariate analysis (PCA, UPGMA) of morphological traits distinguished two continental Bosnian populations from the remaining populations. AFLP analysis separated the investigated populations into two groups based primarily on geographical distance. Essential oil analysis showed a total of 52 compounds, with two chemotypes distinguished based on the essential oil profile. The first was a sesquiterpene chemotype, with \&beta;-caryophyllene, germacrene D or caryophyllene oxide as the major compounds, while the second was an oxygenated monoterpene chemotype, with pulegone and piperitone oxide as the main components. The Mantel test showed a stronger correlation between the morphological traits and AFLP than between the essential oil profile and AFLP. The test also showed a stronger association between the essential oil profile and geographical position than between the morphological traits and geographical position.</p>
},
	issn = {1873-3700},
	doi = {10.1016/j.phytochem.2015.04.003},
	author = {Kremer, Dario and Bolari{\'c}, Snje{\v z}ana and Ballian, Dalibor and Boguni{\'c}, Faruk and Ste{\v s}evi{\'c}, Danijela and Karlovi{\'c}, Ksenija and Kosalec, Ivan and Vokurka, Ale{\v s} and Vukovi{\'c} Rodr{\'\i}guez, Jadranka and Randi{\'c}, Marko and Bezi{\'c}, Nada and Dunki{\'c}, Valerija}
}
@article {Grayer:2003p1126,
	title = {The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae},
	journal = {Phytochemistry},
	volume = {64},
	number = {2},
	year = {2003},
	month = {Jan},
	pages = {519{\textendash}528},
	abstract = {A survey of leaf surface constituents in the family Lamiaceae using HPLC with diode array detection revealed the presence of two characteristic phenolic compounds in many species. The distribution of these phenolics in the Lamiaceae was found to be of taxonomic significance, as they were present in the great majority of species investigated for the subfamily Nepetoideae, including representatives of the well-known genera of culinary herbs, mint, rosemary, sage, thyme and basil. In contrast, they were absent from species of the other subfamilies of Lamiaceae studied and from the related families Verbenaceae, Scrophulariaceae, Acanthaceae and Buddlejaceae. The compounds were isolated from Plectranthus crassus and identified by NMR spectroscopy as the known caffeic acid esters (Z,E)-[2-(3,5-dihydroxyphenyl)ethenyl] 3-(3,4-dihydroxyphenyl)-2-propenoate and (Z, E)-[2-(3,4-dihydroxyphenyl)ethenyl] 3-(3,4-dihydroxyplienyl)-2-propenoate, for which the trivial names nepetoidins A and B are proposed. The presence of this pair of caffeic acid esters adds another character to the chemical, palynological and embryological features distinguishing the Nepetoideae from the other subfamilies of Larmaceae and related families, and supports the view that the Nepetoideae are a specialised and monophyletic group within the family. Nepetoidin B was shown to have a greater antioxidant activity than gallic, rosmarinic and caffeic acids, and showed activity as an insect phagostimulant. Both compounds were antifungal. (C) 2003 Elsevier Ltd. All rights reserved.},
	keywords = {(Z, 3-(3, 4-Dihydroxyphenyl)-2-Propenoate, 4-Dihydroxyphenyl)Ethenyl] 3-(3, 5-Dihydroxyphenyl)-Ethenyl], Antifungal, Caffeic Acid Esters, Chemosystematics, E)-[2-(3, Flavones, Free Radical Scavenging Activity, Genera, Insect Phagostimulant, Labiatae, Lamiaceae, Nepetoideae, Ocimum, Plant},
	doi = {10.1016/S0031-9422(03)00192-4},
	url = {http://www.sciencedirect.com/science?_ob=ArticleURL\&_udi=B6TH7-48KV9RR-H\&_user=2139813\&_rdoc=1\&_fmt=\&_orig=search\&_sort=d\&_docanchor=\&view=c\&_acct=C000054276\&_version=1\&_urlVersion=0\&_userid=2139813\&md5=dc13ca6ce980e66e29866bd090cf4f4b},
	author = {RJ Grayer and MR Eckert and NC Veitch and GC Kite and PD Marin and T Kokubun and MSJ Simmonds and AJ Paton}
}
@article {Petersen:2003p1127,
	title = {Molecules of interest - Rosmarinic acid},
	journal = {Phytochemistry},
	volume = {62},
	number = {2},
	year = {2003},
	month = {Jan},
	pages = {121{\textendash}125},
	abstract = {Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. It is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e.g. antiviral, antibacterial, antiinflammatory and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound. The biosynthesis of rosmarinic acid starts with the amino acids L-phenylalanine and L-tyrosine. All eight enzymes involved in the biosynthesis are known and characterised and cDNAs of several of the involved genes have been isolated. Plant cell cultures, e.g. from Coleus blumei or Salvia officinalis, accumulate rosmarinic acid in amounts much higher than in the plant itself (up to 36\% of the cell dry weight). For this reason a biotechnological production of rosmarinic acid with plant cell cultures has been proposed. (C) 2003 Elsevier Science Ltd. All rights reserved.},
	keywords = {Antioxidant, Biosynthesis, Boraginaceae, Cafeic Acid Esters, Cell-Suspension Cultures, Coleus-Blumei, Growth, Lamiaceae, Pathway, Plant Cell Cultures, Rosmarinic Acid},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000180951600001\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {M Petersen and MSJ Simmonds}
}
@article {Willits:2004p8030,
	title = {Bio-fermentation of modified flavonoids: an example of in vivo diversification of secondary metabolites},
	journal = {Phytochemistry},
	volume = {65},
	number = {1},
	year = {2004},
	month = {Jan},
	pages = {31{\textendash}41},
	abstract = {A bio-fermentation technique was used for the in vivo diversification of flavonoid structures based on expression in Escherichia coli of six O-methyltransferases (OMTs) from Mentha x piperita and one O-glucosyltransferase (GT) each from Arabidopsis thaliana and Allium cepa. Enzymes were shown to be regio-specific in in vitro experiments and modified a broad range of flavonoid substrates at various positions. Using the flavonol quercetin as a model substrate, we show that the product spectrum produced with the in vivo approach is identical to that found in vitro. Additionally, using mixed cultures of E. coli expressing different classes of modifying genes (OMTs and GTs), the production of polymethylated flavonoid glucosides was observed. This report demonstrates the potential to increase the structural diversity of plant secondary metabolites using a multi-enzyme, bio-fermentation approach.},
	keywords = {Amino Acid Sequence, Arabidopsis, Cloning: Molecular, Consensus Sequence, Escherichia coli, Fermentation, Flavonoids, Glucosyltransferases, Mentha piperita, Methyltransferases, Molecular Sequence Data, Onions, Phylogeny, Recombinant Proteins, Sequence Alignment, Sequence Homology: Amino Acid, Stereoisomerism, Substrate Specificity},
	author = {Michael G Willits and Ma{\"{\i}t{\'e} Giovanni and Rogerio T N Prata and Catherine M Kramer and Vincenzo De Luca and John C Steffens and Gerson Graser}
}
@article {Zaidi:1998p1135,
	title = {Free flavonoid aglycones from leaves of Mentha pulegium and Mentha suaveolens (Labiatae)},
	journal = {Phytochemistry},
	volume = {48},
	number = {6},
	year = {1998},
	month = {Jan},
	pages = {991{\textendash}994},
	abstract = {Methoxyflavone aglycones were isolated from the leaf surface of Mentha suaveolens and M. pulegium. 5,7-Dihydroxy-6-methoxy- and 5,6-dihydroxy-7-methoxyflavones with a substituted B-ring and 5,6-dihydroxy-7,8-dimethoxyflavones, characteristic flavonoid constituents of the subfamily Nepetoideae and of the tribe Saturejeae, respectively, were observed in both species. Mentha suaveolens showed considerable chemical variation between samples from Spain and Algeria. (C) 1998 Elsevier Science Ltd. All rights reserved.},
	keywords = {Chemotaxonomy, Chemotypes, External Flavones, Labiatae, Mentha, X-Piperita},
	author = {F Zaidi and B Voirin and M Jay and MR Viricel}
}
@article {Wink:2003p243,
	title = {Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective},
	journal = {Phytochemistry},
	volume = {64},
	number = {1},
	year = {2003},
	pages = {3{\textendash}19},
	author = {M Wink}
}
@article {Alipieva:2003p8026,
	title = {Benzoxazinoids and iridoid glucosides from four Lamium species},
	journal = {Phytochemistry},
	volume = {64},
	number = {8},
	year = {2003},
	month = {Dec},
	pages = {1413{\textendash}7},
	abstract = {A new class of compounds for the plant family Lamiaceae, benzoxazinoids, was found in Lamium galeobdolon. From the aerial parts of the species were isolated the new 2-O-beta-D-glucopyranosyl-6-hydroxy-2H-1,4-benzoxazin-3(4H)-one (6-hydroxy blepharin) together with four known benzoxazinoids, DHBOA-Glc, blepharin, DIBOA, DIBOA-Glc, as well as harpagide, 8-O-acetyl-harpagide and salidroside. Eight known iridoid glucosides, 24-epi-pterosterone and verbascoside were isolated from Lamium amplexicaule, L. purpureum and L. garganicum. The iridoids, 5-deoxylamiol and sesamoside, as well as the phytoecdysone, 24-epi-pterosterone, were found for the first time for the genus Lamium. The phytochemical data are discussed from a systematic and evolutionary point of view.},
	keywords = {Ecdysone, Iridoids, Lamiaceae, Molecular Structure, Nuclear Magnetic Resonance: Biomolecular, Oxazines, Phylogeny, Phytosterols},
	author = {Kalina I Alipieva and Rilka M Taskova and Ljubka N Evstatieva and Nedjalka V Handjieva and Simeon S Popov}
}
@article {Marin:2001p1171,
	title = {Acacetin glycosides as taxonomic markers in Calamintha and Micromeria},
	journal = {Phytochemistry},
	volume = {58},
	number = {6},
	year = {2001},
	month = {Jan},
	pages = {943{\textendash}947},
	abstract = {A new acetylated flavone glycoside, acacetin 7-O-[6{\textquoteright}{\textquoteright}{\textquoteright}{\textquoteright}-O-atcetylglucosyl(1{\textquoteright}{\textquoteright}{\textquoteright}{\textquoteright}{\textendash}>2 ")]rhamnosyl(1{\textquoteright}{\textquoteright}{\textquoteright}{\textendash}>6 " )glucoside, has been isolated from the leaves of Calamintha glandulosa. together with the known compound acacetin 7-O-rhamnosyl(1{\textquoteright}{\textquoteright}{\textquoteright}{\textendash}>6 " )glucoside. The occurrence of these flavonoids in the closely related genera Satureja, Micromeria, Acinos and Clinopodium indicates that their distribution may be of taxonomic significance. (C) 2001 Elsevier Science Ltd. All rights reserved.},
	keywords = {Acacetin 7-O-[6 {\textquoteright}{\textquoteright}{\textquoteright}{\textquoteright}-O-Acetylglucosyl(1 {\textquoteright}{\textquoteright}{\textquoteright}{\textquoteright}-> 2 {\textquoteright}{\textquoteright})]Rhamnosyl(1 {\textquoteright}{\textquoteright}{\textquoteright}-> 6 {\textquoteright}{\textquoteright})Glucoside, Acacetin 7-O-Rhamnosyl(1 {\textquoteright}{\textquoteright}{\textquoteright}-> 6 {\textquoteright}{\textquoteright})Glucoside (Linarin), Calamintha Glandulosa, Chemosystematics, Lamiaceae, Micromeria},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000172499300015\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {PD Marin and RJ Grayer and NC Veitch and GC Kite and JB Harborne}
}
@article {FIRMAGE:1979p1151,
	title = {EFFECT OF DEVELOPMENT ON MONOTERPENE COMPOSITION OF HEDEOMA-DRUMMONDII},
	journal = {Phytochemistry},
	volume = {18},
	number = {11},
	year = {1979},
	month = {Jan},
	pages = {1827{\textendash}1829},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=A1979HS65400013\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {DH FIRMAGE and R IRVING}
}
