@booklet {Park:2008p1122,
	title = {Biotechnological applications for rosmarinic acid production in plant},
	howpublished = {Afr J Biotechnol},
	volume = {7},
	number = {25},
	year = {2008},
	month = {Jan},
	pages = {4959{\textendash}4965},
	abstract = {Rosmarinic acid, an important phenolic compound, is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e. g. antiviral, antibacterial, anti-inflammatory, and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound. The biosynthesis of rosmarinic acid starts with the amino acids phenylalanine and tyrosine. Plant cell cultures, e. g. from Coleus blumei or Salvia officinalis, accumulate rosmarinic acid in amounts much higher than in the plant itself (up to 36\% of the cell dry weight). Similarly some other biotechnological researches for production of rosmarinic acid were done in the past i.e. from shoot culture, producing hairy root, using bioreactor, and the treatment of elicitors. As a review paper the aim of this study is to gather all the possible biotechnological ways to produce rosmarinic acid, thus will help the scientists to take action for future study in this discipline.},
	keywords = {Agastache-Rugosa Kuntze, Anchusa-Officinalis, Biotechnology, Cell-Suspension Cultures, Coleus-Blumei Cells, Hairy Root Cultures, Hyssopus-Officinalis, In Vitro Culture, Ocimum-Basilicum, Oregano Origanum-Vulgare, Phenolic-Compounds, Plant, Rosmarinic Acid, Salvia-Officinalis},
	author = {Sang Un Park and Md Romij Uddin and Hui Xu and Yong Kyoung Kim and Sook Young Lee}
}
@article {Janicsak:2006p1123,
	title = {Study of the oleanolic and ursolic acid contents of some species of the Lamiaceae},
	journal = {Biochem Syst Ecol},
	volume = {34},
	number = {5},
	year = {2006},
	month = {Jan},
	pages = {392{\textendash}396},
	abstract = {The oleanolic and ursolic acid contents from 88 taxa. of Lamiaceae (19 genera, 66 species, 8 subspecies, 9 varieties and 5 hybrids) were investigated using gas chromatography. Both triterpenoid acids were present in all of the investigated taxa, but the plants belonging in the subfamily Nepetoideae produced significantly higher amounts than those in the subfamily Lamioideae. The oleanolic acid content ranged from traces to 1.840\% dry weight, and that of ursolic acid from traces to 4.019\% dry weight. (c) 2006 Elsevier Ltd. All rights reserved.},
	keywords = {Chemotaxonomy, Constituents, Diterpenoids, Gas Chromatography, Herb, Labiatae, Lamiaceae, Mice, Oleanolic Acid, Pentacyclic Triterpenes, Salvia-Officinalis, Subfamily Lamioideae, Subfamily Nepetoideae, Triterpenoids, Ursolic Acid},
	doi = {10.1016/j.bse.2005.12.004},
	url = {http://www.sciencedirect.com/science?_ob=ArticleURL\&_udi=B6T4R-4JCBPHY-1\&_user=2139813\&_rdoc=1\&_fmt=\&_orig=search\&_sort=d\&_docanchor=\&view=c\&_acct=C000054276\&_version=1\&_urlVersion=0\&_userid=2139813\&md5=0fa9d49fb0d0eed1c4653613967dc834},
	author = {G Janicsak and K Veres and AZ Kakasy and I Mathe}
}
@article {ViverosValdez:2008p1147,
	title = {Free radical scavengers from the Mexican herbal tea "Poleo" (Hedeoma drummondii)},
	journal = {Z Naturforsch C},
	volume = {63},
	number = {5-6},
	year = {2008},
	month = {Jan},
	pages = {341{\textendash}346},
	abstract = {The aerial parts of the Lamiaceae Hedeonia drummondii (Benth.) are used in Mexico to prepare a herbal tea and by North American Amerindians as a spice. The methanolic extract of the aerial parts exhibited a strong antioxidant effect measured by the scavenging of the free diphenyl picrylhydrazyl (DPPH) radical. Assay-guided fractionation of the crude methanolic extract allowed the identification of three major active constituents, chlorogenic, caffeic and rosmarinic acid, as welt as sideritoflavone derivatives and simple phenolics. The TEAC, FRAP, total phenolic and flavonoid content were determined. The high content of caffeic acid and rosmarinic acid relates to the antioxidant activity of H. drummondii.},
	keywords = {Antioxidant Activity, Caffeic Acid, Chlorogenic Acid, Diseases, Extracts, Free Radical Scavengers, Hedeoma Drummondii, Lamiaceae, Plants, Rosmarinic Acid, Salvia-Officinalis, Vegetables},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000257377200006\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {Ezequiel Viveros-Valdez and Catalina Rivas-Morales and Pilar Carranza-Rosales and Sandra Mendoza and Guillermo Schmeda-Hirschmann}
}
