@article {Grayer:2003p1126,
	title = {The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae},
	journal = {Phytochemistry},
	volume = {64},
	number = {2},
	year = {2003},
	month = {Jan},
	pages = {519{\textendash}528},
	abstract = {A survey of leaf surface constituents in the family Lamiaceae using HPLC with diode array detection revealed the presence of two characteristic phenolic compounds in many species. The distribution of these phenolics in the Lamiaceae was found to be of taxonomic significance, as they were present in the great majority of species investigated for the subfamily Nepetoideae, including representatives of the well-known genera of culinary herbs, mint, rosemary, sage, thyme and basil. In contrast, they were absent from species of the other subfamilies of Lamiaceae studied and from the related families Verbenaceae, Scrophulariaceae, Acanthaceae and Buddlejaceae. The compounds were isolated from Plectranthus crassus and identified by NMR spectroscopy as the known caffeic acid esters (Z,E)-[2-(3,5-dihydroxyphenyl)ethenyl] 3-(3,4-dihydroxyphenyl)-2-propenoate and (Z, E)-[2-(3,4-dihydroxyphenyl)ethenyl] 3-(3,4-dihydroxyplienyl)-2-propenoate, for which the trivial names nepetoidins A and B are proposed. The presence of this pair of caffeic acid esters adds another character to the chemical, palynological and embryological features distinguishing the Nepetoideae from the other subfamilies of Larmaceae and related families, and supports the view that the Nepetoideae are a specialised and monophyletic group within the family. Nepetoidin B was shown to have a greater antioxidant activity than gallic, rosmarinic and caffeic acids, and showed activity as an insect phagostimulant. Both compounds were antifungal. (C) 2003 Elsevier Ltd. All rights reserved.},
	keywords = {(Z, 3-(3, 4-Dihydroxyphenyl)-2-Propenoate, 4-Dihydroxyphenyl)Ethenyl] 3-(3, 5-Dihydroxyphenyl)-Ethenyl], Antifungal, Caffeic Acid Esters, Chemosystematics, E)-[2-(3, Flavones, Free Radical Scavenging Activity, Genera, Insect Phagostimulant, Labiatae, Lamiaceae, Nepetoideae, Ocimum, Plant},
	doi = {10.1016/S0031-9422(03)00192-4},
	url = {http://www.sciencedirect.com/science?_ob=ArticleURL\&_udi=B6TH7-48KV9RR-H\&_user=2139813\&_rdoc=1\&_fmt=\&_orig=search\&_sort=d\&_docanchor=\&view=c\&_acct=C000054276\&_version=1\&_urlVersion=0\&_userid=2139813\&md5=dc13ca6ce980e66e29866bd090cf4f4b},
	author = {RJ Grayer and MR Eckert and NC Veitch and GC Kite and PD Marin and T Kokubun and MSJ Simmonds and AJ Paton}
}
@article {Petersen:2003p1127,
	title = {Molecules of interest - Rosmarinic acid},
	journal = {Phytochemistry},
	volume = {62},
	number = {2},
	year = {2003},
	month = {Jan},
	pages = {121{\textendash}125},
	abstract = {Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. It is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e.g. antiviral, antibacterial, antiinflammatory and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound. The biosynthesis of rosmarinic acid starts with the amino acids L-phenylalanine and L-tyrosine. All eight enzymes involved in the biosynthesis are known and characterised and cDNAs of several of the involved genes have been isolated. Plant cell cultures, e.g. from Coleus blumei or Salvia officinalis, accumulate rosmarinic acid in amounts much higher than in the plant itself (up to 36\% of the cell dry weight). For this reason a biotechnological production of rosmarinic acid with plant cell cultures has been proposed. (C) 2003 Elsevier Science Ltd. All rights reserved.},
	keywords = {Antioxidant, Biosynthesis, Boraginaceae, Cafeic Acid Esters, Cell-Suspension Cultures, Coleus-Blumei, Growth, Lamiaceae, Pathway, Plant Cell Cultures, Rosmarinic Acid},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000180951600001\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {M Petersen and MSJ Simmonds}
}
