@booklet {Park:2008p1122,
	title = {Biotechnological applications for rosmarinic acid production in plant},
	howpublished = {Afr J Biotechnol},
	volume = {7},
	number = {25},
	year = {2008},
	month = {Jan},
	pages = {4959{\textendash}4965},
	abstract = {Rosmarinic acid, an important phenolic compound, is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e. g. antiviral, antibacterial, anti-inflammatory, and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound. The biosynthesis of rosmarinic acid starts with the amino acids phenylalanine and tyrosine. Plant cell cultures, e. g. from Coleus blumei or Salvia officinalis, accumulate rosmarinic acid in amounts much higher than in the plant itself (up to 36\% of the cell dry weight). Similarly some other biotechnological researches for production of rosmarinic acid were done in the past i.e. from shoot culture, producing hairy root, using bioreactor, and the treatment of elicitors. As a review paper the aim of this study is to gather all the possible biotechnological ways to produce rosmarinic acid, thus will help the scientists to take action for future study in this discipline.},
	keywords = {Agastache-Rugosa Kuntze, Anchusa-Officinalis, Biotechnology, Cell-Suspension Cultures, Coleus-Blumei Cells, Hairy Root Cultures, Hyssopus-Officinalis, In Vitro Culture, Ocimum-Basilicum, Oregano Origanum-Vulgare, Phenolic-Compounds, Plant, Rosmarinic Acid, Salvia-Officinalis},
	author = {Sang Un Park and Md Romij Uddin and Hui Xu and Yong Kyoung Kim and Sook Young Lee}
}
@article {Kim:2009p1158,
	title = {In vitro alpha-Glucosidase Inhibitory Potential and Antioxidant Activity of Selected Lamiaceae Species Inhabited in Korean Penninsula},
	journal = {Food Sci Biotechnol},
	volume = {18},
	number = {1},
	year = {2009},
	month = {Jan},
	pages = {239{\textendash}244},
	abstract = {In the current study, inhibitory activity of 8 selected Korean edible plants of Lamiaceae family against alpha-glucosidases, prepared from rat small intestine acetone powder was evaluated. Total flavonoids and oxygen radical absorbance capacity (ORAC) were also investigated. Methyl alcohol extracts of Scutellaria indica (SI) had the highest alpha-glucosidase inhibitory activity relevant for potentially managing hyperglycemia, followed by Clinopodium gracile (CG) and Thymus quinquecostatus (TQ). These 3 species also showed significant antioxidant activity in ORAC system. The alpha-glucosidase inhibitory activity of the extracts was compared to selected phenolics. Among the standard phenolics tested quercetin which was major flavonoid in the extracts had the highest alpha-glucosidase inhibitory activity. CG, TQ, and SI which had high quercetin content and ORAC values also exhibited significant sucrase inhibitory activity. Results suggested that selected 3 Korean Lamiaceae species have the potential development of effective dietary strategy for postprandial hyperglycemia and oxidative stress-linked diabetes complications.},
	keywords = {Antioxidant, Assay, Cancer, Capacity, Disease, Extracts, Fruit, Glucosidase Inhibitor, Lamiaceae, Non-Insulin Dependent Diabetes Mellitus, Oxygen Radical Absorbance Capacity, Phenolic-Compounds, Plasma, Risk, Vegetables},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000263843200041\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {Dong-Soo Kim and Hyun Jeong Kwon and Hae-Dong Jang and Young-In Kwon}
}
