@article {Grayer:2003p1126,
	title = {The chemotaxonomic significance of two bioactive caffeic acid esters, nepetoidins A and B, in the Lamiaceae},
	journal = {Phytochemistry},
	volume = {64},
	number = {2},
	year = {2003},
	month = {Jan},
	pages = {519{\textendash}528},
	abstract = {A survey of leaf surface constituents in the family Lamiaceae using HPLC with diode array detection revealed the presence of two characteristic phenolic compounds in many species. The distribution of these phenolics in the Lamiaceae was found to be of taxonomic significance, as they were present in the great majority of species investigated for the subfamily Nepetoideae, including representatives of the well-known genera of culinary herbs, mint, rosemary, sage, thyme and basil. In contrast, they were absent from species of the other subfamilies of Lamiaceae studied and from the related families Verbenaceae, Scrophulariaceae, Acanthaceae and Buddlejaceae. The compounds were isolated from Plectranthus crassus and identified by NMR spectroscopy as the known caffeic acid esters (Z,E)-[2-(3,5-dihydroxyphenyl)ethenyl] 3-(3,4-dihydroxyphenyl)-2-propenoate and (Z, E)-[2-(3,4-dihydroxyphenyl)ethenyl] 3-(3,4-dihydroxyplienyl)-2-propenoate, for which the trivial names nepetoidins A and B are proposed. The presence of this pair of caffeic acid esters adds another character to the chemical, palynological and embryological features distinguishing the Nepetoideae from the other subfamilies of Larmaceae and related families, and supports the view that the Nepetoideae are a specialised and monophyletic group within the family. Nepetoidin B was shown to have a greater antioxidant activity than gallic, rosmarinic and caffeic acids, and showed activity as an insect phagostimulant. Both compounds were antifungal. (C) 2003 Elsevier Ltd. All rights reserved.},
	keywords = {(Z, 3-(3, 4-Dihydroxyphenyl)-2-Propenoate, 4-Dihydroxyphenyl)Ethenyl] 3-(3, 5-Dihydroxyphenyl)-Ethenyl], Antifungal, Caffeic Acid Esters, Chemosystematics, E)-[2-(3, Flavones, Free Radical Scavenging Activity, Genera, Insect Phagostimulant, Labiatae, Lamiaceae, Nepetoideae, Ocimum, Plant},
	doi = {10.1016/S0031-9422(03)00192-4},
	url = {http://www.sciencedirect.com/science?_ob=ArticleURL\&_udi=B6TH7-48KV9RR-H\&_user=2139813\&_rdoc=1\&_fmt=\&_orig=search\&_sort=d\&_docanchor=\&view=c\&_acct=C000054276\&_version=1\&_urlVersion=0\&_userid=2139813\&md5=dc13ca6ce980e66e29866bd090cf4f4b},
	author = {RJ Grayer and MR Eckert and NC Veitch and GC Kite and PD Marin and T Kokubun and MSJ Simmonds and AJ Paton}
}
@booklet {Park:2008p1122,
	title = {Biotechnological applications for rosmarinic acid production in plant},
	howpublished = {Afr J Biotechnol},
	volume = {7},
	number = {25},
	year = {2008},
	month = {Jan},
	pages = {4959{\textendash}4965},
	abstract = {Rosmarinic acid, an important phenolic compound, is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e. g. antiviral, antibacterial, anti-inflammatory, and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound. The biosynthesis of rosmarinic acid starts with the amino acids phenylalanine and tyrosine. Plant cell cultures, e. g. from Coleus blumei or Salvia officinalis, accumulate rosmarinic acid in amounts much higher than in the plant itself (up to 36\% of the cell dry weight). Similarly some other biotechnological researches for production of rosmarinic acid were done in the past i.e. from shoot culture, producing hairy root, using bioreactor, and the treatment of elicitors. As a review paper the aim of this study is to gather all the possible biotechnological ways to produce rosmarinic acid, thus will help the scientists to take action for future study in this discipline.},
	keywords = {Agastache-Rugosa Kuntze, Anchusa-Officinalis, Biotechnology, Cell-Suspension Cultures, Coleus-Blumei Cells, Hairy Root Cultures, Hyssopus-Officinalis, In Vitro Culture, Ocimum-Basilicum, Oregano Origanum-Vulgare, Phenolic-Compounds, Plant, Rosmarinic Acid, Salvia-Officinalis},
	author = {Sang Un Park and Md Romij Uddin and Hui Xu and Yong Kyoung Kim and Sook Young Lee}
}
@article {Oliveira:2007p1317,
	title = {Molecular phylogeny, biogeography, and systematics of Dicerandra (Lamiaceae), a genus endemic to the southeastern United States{\textquoteright}},
	journal = {Am J Bot},
	volume = {94},
	number = {6},
	year = {2007},
	month = {Jan},
	pages = {1017{\textendash}1027},
	abstract = {Dicerandra, an endemic mint of the southeastern United States, comprises nine species, all of which are threatened or endangered and restricted to sandhill vegetation and a mosaic of scrub habitats. Molecular phylogenetic analyses of Dicerandra based on data from the nuclear and plastid genomes for all 13 taxa of the genus, identified two strongly supported clades, corresponding to the four annual and to the five perennial species of Dicerandra. However, the nuclear and plastid trees were incongruent in their placement of two perennial taxa, D. cornutissima and D. immaculata var. savannarum, perhaps due to ancient hybridization or to lineage sorting. Based on these analyses, the widespread D. linearifolia is not monophyletic, with populations of D. linearifolia var. linearifolia falling into either western or eastern clades. The western clade, comprising populations of D. linearifolia var. linearifolia and var. robustior, occurs in an area drained by rivers flowing toward the Gulf of Mexico, whereas the eastern clade, comprising populations of D. linearifolia var. linearifolia, D. densiflora, D. odoratissima, and D. radfordiana (i.e., all the annual species), occupies a region drained by rivers flowing to the Atlantic Ocean. Although this pattern of genetic differentiation between populations from these two river drainages has been documented in several animal species, it has not previously been reported for plants. A revised subgeneric classification is presented to reflect the annual and perennial clades.},
	keywords = {Biogeography, Chloroplast Dna, Conservation, Dicerandra, Endemic Species, Florida, Inferences, Internal Transcribed Spacer, Labiatae, Lake Wales Ridge, Matk, Plant, Sequences, Trnt-Trnl},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000249830600013\&SID=2ABa3P2LDb\%2540FhI56hhg\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_i},
	author = {Luiz O Oliveira and Robin B Huck and Matthew A Gitzendanner and Walter S Judd and Douglas E Soltis and Pamela S Soltis}
}
@article {Dzhambazov:2002p1174,
	title = {In vitro screening for antitumour activity of Clinopodium vulgare L. (Lamiaceae) extracts},
	journal = {Biol Pharm Bull},
	volume = {25},
	number = {4},
	year = {2002},
	month = {Jan},
	pages = {499{\textendash}504},
	abstract = {Aqueous extract of Clinopodium vulgare L. showed strong antitumour activity when tested in vitro on A2058 (human metastatic melanoma), HEp-2 (epidermoid carcinoma, larynx, human) and L5178Y (mouse lymphoma) cell lines-6 h after treatment disintegration of the nuclei and cell lysis started. Applied at a concentration of 80 mug/ml it reduced the cell survival to 1.0, 5.6 and 6.6\%, respectively. The concentrations of aqueous extract inhibiting the growth of A2058, HEp-2 and L5178Y cells by 50\% (IC50 values) were calculated to be 20, 10 and 17.8 mug/ml respectively. Two groups of active substances were detected: the first one, probably combining glycosides, influenced adhesion, while the second one caused massive cell vacuolisation. The chloroform extract, which contained ursolic acid and gentriacontan had also cytotoxic, however a little bit weaker effect. All changes observed were irreversible.},
	keywords = {Antitumour Activity, Chinensis, Clinopodium Vulgare L., Hela-Cells, Induced Phospholipid-Metabolism, Inhibitory Activity, Oleanane-Triterpene Saponins, Plant, Plant Extract, Steroidal Saponins, Ursolic Acid},
	url = {http://apps.isiknowledge.com/InboundService.do?product=WOS\&action=retrieve\&SrcApp=Papers\&UT=000174690200019\&SID=2AFL5dnj5MCc8JPedL5\&SrcAuth=mekentosj\&mode=FullRecord\&customersID=mekentosj\&DestFail=http\%253A\%252F\%252Faccess.isiproducts.com\%252Fcustom_image},
	author = {B Dzhambazov and S Daskalova and A Monteva and N Popov}
}
